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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4329 | CP 376395 | CP-316311 | CRFR |
CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist. | |||
T12492 | Pivagabine | CXB-722 | GABA Receptor |
Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats. It counteracts the impact of foot shock on GABAA receptor... | |||
T7361 | Verucerfont | NBI77860,GSK561679 | CRFR |
Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) . | |||
TP1021 | Urocortin, human | Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I | CRFR |
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF). | |||
T31095 | Crinecerfont | SSR125543,SSR 125543,SSR-125543,SSR125543A,SSR 125543A,SSR-125543A | CRFR |
Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia. | |||
T16475 | Pexacerfont | BMS-562086 | CRFR |
Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor). | |||
TP1448L | Astressin acetate | Astressin acetate (170809-51-5 Free base) | CRFR |
Astressin acetate is an antagonist of corticotropin releasing factor (CRF) with low affinity for the CRF binding protein and high affinity for the cloned pituitary receptor(Ki = 2 nM). | |||
T27227 | E2508 | E 2508,E-2508 | |
E2508 is a selective antagonist of corticotropin-releasing factor 1 receptor. | |||
T12276 | NVS-CRF38 | Others | |
NVS-CRF38 is an antagonist of corticotropin-releasing factor receptor 1 (CRF1). | |||
T26856 | BMS-764459 | ||
BMS-764459 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1). | |||
T15214 | Emicerfont | GW876008 | Others |
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM). | |||
T25864 | NGD9002 | NGD-9002,NGD 9002 | |
NGD9002 is a novel generation, topology 2 selective corticotropin releasing factor-1 (CRF-1) receptor antagonist agent. | |||
T71294 | BMS-763534 | ||
BMS-763534 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1). | |||
T69248 | ONO-2333 | ||
ONO-2333 is a corticotropin-releasing factor receptor antagonist, for the treatment of depression and/or anxiety disorders | |||
T23067 | NGD 98-2 hydrochloride | Others | |
corticotropin-releasing factor receptor 1 (CRF1) antagonist | |||
T69374 | NGD 98-2 | ||
NGD 98-2 is a new generation, topology 2 selective orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist. | |||
T38228 | R 121919 hydrochloride | ||
High affinity corticotropin releasing factor receptor1 (CRF1) antagonist (Ki = 3.5 nM). Reduces stress-induced elevations of plasma ACTH. Anxiolytic and antidepressant in vivo. Orally bioavailable. Chen and Grigoriadis (... | |||
TP1860 | Urocortin II, human | ||
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor. | |||
TP2048 | α-Helical CRF(9-41) | α-helical CRF 9-41 | |
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively). | |||
TP2095 | Astressin 2B | ||
Potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist (IC50 values are 1.3 and > 500 nM for CRF2 and CRF1 respectively). Antagonizes CRF2-mediated inhibition of gastric emptying. |