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Search Results for " corticotropin-releasing factor receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T4329 CP 376395 CP-316311 CRFR
CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.
T12492 Pivagabine CXB-722 GABA Receptor
Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats. It counteracts the impact of foot shock on GABAA receptor...
T7361 Verucerfont NBI77860,GSK561679 CRFR
Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .
TP1021 Urocortin, human Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I CRFR
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
T31095 Crinecerfont SSR125543,SSR 125543,SSR-125543,SSR125543A,SSR 125543A,SSR-125543A CRFR
Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia.
T16475 Pexacerfont BMS-562086 CRFR
Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).
TP1448L Astressin acetate Astressin acetate (170809-51-5 Free base) CRFR
Astressin acetate is an antagonist of corticotropin releasing factor (CRF) with low affinity for the CRF binding protein and high affinity for the cloned pituitary receptor(Ki = 2 nM).
T27227 E2508 E 2508,E-2508
E2508 is a selective antagonist of corticotropin-releasing factor 1 receptor.
T12276 NVS-CRF38 Others
NVS-CRF38 is an antagonist of corticotropin-releasing factor receptor 1 (CRF1).
T26856 BMS-764459
BMS-764459 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).
T15214 Emicerfont GW876008 Others
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).
T25864 NGD9002 NGD-9002,NGD 9002
NGD9002 is a novel generation, topology 2 selective corticotropin releasing factor-1 (CRF-1) receptor antagonist agent.
T71294 BMS-763534
BMS-763534 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).
T69248 ONO-2333
ONO-2333 is a corticotropin-releasing factor receptor antagonist, for the treatment of depression and/or anxiety disorders
T23067 NGD 98-2 hydrochloride Others
corticotropin-releasing factor receptor 1 (CRF1) antagonist
T69374 NGD 98-2
NGD 98-2 is a new generation, topology 2 selective orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.
T38228 R 121919 hydrochloride
High affinity corticotropin releasing factor receptor1 (CRF1) antagonist (Ki = 3.5 nM). Reduces stress-induced elevations of plasma ACTH. Anxiolytic and antidepressant in vivo. Orally bioavailable. Chen and Grigoriadis (...
TP1860 Urocortin II, human
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor.
TP2048 α-Helical CRF(9-41) α-helical CRF 9-41
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
TP2095 Astressin 2B
Potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist (IC50 values are 1.3 and > 500 nM for CRF2 and CRF1 respectively). Antagonizes CRF2-mediated inhibition of gastric emptying.
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